Open AccessANALGESIC, ANTI-INFLAMMATORY, ANTIPYRETIC EVALUATION OF ETHANOLIC EXTRACT OF LEAF OF POLYALTHIA LONGIFOLIA
Author(s) -
S Ramjith.U.,
Faby Salim,
S Ashamol.K.,
Cyril Mathews Jacob
Publication year - 2021
Publication title -
journal of biomedical and pharmaceutical research
Language(s) - English
Resource type - Journals
eISSN - 2589-8752
pISSN - 2279-0594
DOI - 10.32553/jbpr.v10i3.866
Subject(s) - analgesic , hot plate , antipyretic , acetic acid , traditional medicine , chemistry , anti inflammatory , pharmacology , medicine , organic chemistry , materials science , composite material
Polyalthia longifolia leaves ethanolic extracts produced significant analgesic activity in both Hot plate and acetic acid induced writhing models in mice. In hot plate method percentage increase in reaction time was determined where as in acetic acid induced writhing model percentage decrease in writhings was determined. From the results obtained it can be concluded that Polyalthia longifolia leaves has analgesic, anti inflammatory and antipyretic activity.
Keywords: Analgesic, Anti-inflammatory, Antipyretic, Hot plate method, Acetic acid induced writhing model.