Open AccessGRINSPAN SYNDROME: THE TRIAD
Author(s) -
M Seema,
S. Srinivasan
Publication year - 2020
Publication title -
international journal of medical science and diagnosis research
Language(s) - English
Resource type - Journals
eISSN - 2589-7837
pISSN - 2581-3935
DOI - 10.32553/ijmsdr.v4i10.683
Subject(s) - medicine , oral lichen planus , diabetes mellitus , dermatology , complication , swallowing , mucocutaneous zone , exacerbation , malignant transformation , disease , surgery , pathology , endocrinology
Lichen Planus is a chronic immunologically mediated mucocutaneous disorder with varied clinical manifestations. The condition might be associated with multiple causative or exacerbation factors. An interesting association of Oral Lichen Planus with Diabetes Mellitus and vascular hypertension is called as Grinspan's syndrome. Since its inception has been an arena of interest. It has appeared very lucrative to many researchers as it lacks clarity and enhanced ambiguity. A 65 year female patient came with a complaint of burning mouth and difficulty in swallowing since 1 year with H/O Diabetes Mellitus since 8years and hypertension since 2 years. Malignant transformation is the most significant complication of long standing and non healing Lichen Planus. Repeated follow up and biopsies are mandatory for prevention and early detection of malignant transformation.
Keywords: Grinspan Syndrome, Hypertrophic Lichen Planus, Esophageal Lichen Planus