Open AccessDry Eye and Antipsychotic Drug
Author(s) -
Sunita Khurana,
Seema Rajvanshi
Publication year - 2022
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v6i3.2466
Subject(s) - anticholinergic , medicine , antipsychotic , schizophrenia (object oriented programming) , drug , antipsychotic drug , regimen , atypical antipsychotic , psychiatry
Background: To study the dry eye prevalence in patients on chronic antipsychotic therapy.
Methods: 50 patients who were diagnosed of schizophrenia and have been under anti-pschyotic were included.
Results: 17 patients out of 50 patients on anti-psychotic medications for more than 2 years had dry eye disease. Of the 100 eyes evaluated, 30 eyes were found to have dry eye disease. Patients on two drug regimen showed more prevalence of dry eye than on mono drug regimen in our study.
Conclusion: Anti-psychotic drug may induce dry eye syndrome and thus may lead to morphological alterations in corneal parameters through its anticholinergic and antidopaminergic activities.
Keywords: Dry eye, Prevalence, Antipsychotic