Open AccessA STUDY OF HYPERURICACIDEMIA AND THE PRESENCE AND SEVERITY OF ACUTE CORONARY SYNDROME IN INDEX MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTER, INDORE ( M.P.)
Author(s) -
Bushra Khanam,
Mahmood Khan,
Ajay Kumar Singh,
Sumit Solanki,
S.M. Holkar
Publication year - 2021
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v5i7.2029
Subject(s) - medicine , acute coronary syndrome , asymptomatic , coronary angiography , cardiology , stenosis , uric acid , population study , population , myocardial infarction , environmental health
Background: Few studies have assessed the relation of hyperuricacidemia with the acute coronary syndrome (ACS). This study investigated the association between high uric acid levels with the presence and severity of ACS.
Methods: Three hundred and seventy patients having angiographic evidence of atherosclerosis (CAD + case group) compared to 170 patients with no luminal stenosis (n=110) or with <50% luminal stenosis (n=60) at coronary angiography (CAD – control group).
Results: The mean age of the patients was 60 ± 10 years (317 men, 58.7%). Hyperuricacidemia was more likely associated with a trend toward higher vessel scores, indicating a more severe CAD (adjusted OR=1.51, 95% CI=1.09-2.09; P=0.005) in the whole population. A comparison of sex-specific values showed a significant association existed only in men.
Conclusions: Asymptomatic hyperuricacidemia may be associated with the presence and severity of ACS.
Keywords: Hyperuricacidemia, Severity & Acute Coronary Syndrome.