Open AccessRole of calcium channel blocker in excessive mast cell degranulation
Author(s) -
Sagarika Datta
Publication year - 2021
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v5i7.1981
Subject(s) - degranulation , medicine , mast cell , itching , rash , anxiety , migraine , allergy , calcium channel blocker , fibromyalgia , immunology , dermatology , calcium , receptor , psychiatry
Here, I present a case of a female patient, age 45 years, for whom the uncontrolled mast cell degranulation created many issues related to allergy like, skin rash, itching, breathing discomfort, frequent throat infection, GERD, migraine, fibromyalgia, peripheral neuropathy, depression, anxiety disorder, constipation etc. For the patient, it was observed that calcium channel blockers seem to control the unnecessary and uncontrolled mast cell degranulation. CCB seemed to have a role to play in mast cell degranulation.