Open AccessALTERATION IN SERUM MAGNESIUM LEVELS IN PATIENTS WITH ESSENTIAL HYPERTENSION
Author(s) -
GS Asha,
Jyothi A Natikar,
Sujata Mohanty,
Alapaty Shailaja
Publication year - 2021
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v5i6.1974
Subject(s) - blood pressure , magnesium , medicine , essential hypertension , diastole , pathophysiology , endocrinology , gastroenterology , chemistry , organic chemistry
Essential hypertension (EHTN) accounts for 95% of all cases of hypertension affecting approximately one billion individuals worldwide. Alteration in trace elements like magnesium can be helpful in knowing the elemental involvement in the pathophysiology of EHTN and its associated complications.
Aims and Objectives: 1. To estimate serum levels of magnesium in patients of EHTN and compare it with normotensive healthy subjects. 2. To find the correlation of serum levels of magnesium with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients of EHTN.
Materials and Methods: The study was conducted in 100 subjects, out of which 50 were essential hypertensive patients (cases) and 50 were normotensive healthy subjects (controls), within the age group of 25-65 years. Serum magnesium were measured by using the auto analyzer Beckman Coulter DXC 600. The results were analysed by using students ‘t’ test and pearson’s correlation.
Results: Our study found a significantly (p<0.001**) decreased levels of serum magnesium in cases as compared to controls. Our study also revealed a significant negative correlation between serum magnesium with SBP (r= -0.805, p<0.001**) and DBP (r= -0.395, p=0.005**) among essential hypertensives.
Keywords: EHTN- Essential hypertension, HTN – Hypertension, SBP – Systolic blood pressure, DBP – Diastolic blood pressure