Open AccessTO STUDY THE ROLE OF PLATELET INDICES (MPV, PDW, PCT, PLCR) AS PROGNOSTIC MARKERS IN COMPARISON WITH APACHE II AND SAPS 3 SCORES IN SEVERE SEPSIS
Author(s) -
Ramesh Kumar,
Laxmi Laxmi,
Maniram Kumhar,
Arunarya
Publication year - 2021
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v5i2.1739
Subject(s) - mean platelet volume , medicine , sepsis , apache ii , intensive care unit , platelet , red blood cell distribution width , gastroenterology , severe sepsis , septic shock
Background: Platelet indices including mean platelet volume (MPV), platelet volume distribution width (PDW), plateletcrit (PCT) and platelet large cell ratio (PLCR), these indices can be measured by an inexpensive and readily available routine blood count and may be useful as a prognostic marker in patients with sepsis
Methods: This study was planned to establish platelet indices as a prognostic marker in comparison with APACHE II and SAPS 3 score in severe sepsis patients admitted in Medical Intensive Care Unit under Department of Medicine, Jawahar Lal Nehru Medical College & Hospital, Ajmer.
Results: In our study, higher Mean Platelet Volume(MPV) on day 7 was associated with higher APACHE II score, and this difference was statistically significant (p value-0.001). Also, higher Mean Platelet Volume (MPV) on day 7 was associated with higher SAPS III score, and this difference was statistically significant (p value-0.01).
Conclusion: In developing countries like India platelet indices (specially MPV and PDW) measured on admission and subsequently can be used as prognostic markers in severe sepsis in emergency and critical care setup.
Keywords: MPV, Sepsis, APACHE II, SAPS 3