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The CLINICOPATHOLOGICAL SPECTRUM OF ORAL SQUAMOUS CELL CARCINOMA AMONG TOBACCO CONSUMERS: AN INSTITUTIONAL STUDY
Author(s) -
Kiran Arif,
Fouzia Shaikh,
Faraz Ahmed Baig,
Rizma Khan,
Saba Arif
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i9.1412
Subject(s) - medicine , malignancy , basal cell , etiology , buccal mucosa , disease , buccal administration , stage (stratigraphy) , pathology , chewing tobacco , carcinoma , population , oncology , dermatology , oral cavity , gastroenterology , cancer , dentistry , biology , environmental health , paleontology
Background: Oral squamous cell carcinoma (OSCC) constitutes 90% of all oral malignancies. Tobacco products, viral infections and additional risk factors are common etiological elements for this tumor. Objective: The aim of this study is to analyze the clinicopathological and sociodemographic features of patients diagnosed with oral squamous cell carcinoma. Material and Methods: Histologically confirmed 35 OSCC cases were selected for study. The clinicopathological data was obtained from patients and analyzed using SPSS software version 20. Results: Majority of cases was men and diagnosed with disease during fourth decade of life. Buccal mucosa was the common site while gutka chewing was observed as leading habit among our cases. Also, stage II and moderate histological differentiation was predominant among prognostic indicators of OSCC. Conclusion: Our data suggested that men, gutka consumers and early onset of disease are more prevalent characteristics in oral squamous cell carcinoma cases from our population. Most tumors classically affected buccal mucosa and late diagnosis seems to be common among our cases. Keywords: Malignancy, Squamous Cell Carcinoma, Oral Cavity, Tobacco

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