Open AccessA STUDY TO EVALUATE THE PREVALENCE AND CLINIC-ETIOLOGIC PROFILE OF THROMBOCYTOPENIA IN PREGNANCY: AN OBSERVATIONAL STUDY.
Author(s) -
Sweety Rani,
Anjana Sinha
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i7.1391
Subject(s) - medicine , ecchymosis , hellp syndrome , pregnancy , obstetrics , haemolysis , pediatrics , dengue fever , etiology , eclampsia , medical history , preeclampsia , observational study , family history , surgery , immunology , biology , genetics
Objective: To evaluate the prevalence and clinic-etiologic profile of thrombocytopenia in pregnancy:
Materials and Methods: The present hospital based observational study was conducted in the Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar from July 2016 to January 2017. A detailed obstetrics history was obtained and maternal high risk factors like preeclampsia, eclampsia, DIC, HELLP syndromes etc were noted. Medical history like anemia, malaria, dengue, liver disorder, current or previous bleeding problems, family history of bleeding & transfusion history were noted. Clinical findings suggestive of thrombocytopenia like petechiae, ecchymoses etc. were noted.
Results: Out of total 74 patients, Gestational thrombocytopenia was the most common etiological factor with 41.9% cases followed by 35.1% for hypertensive disorders including HELLP syndrome followed by 6.8% for Malaria and dengue. The most common hemorrhagic presentation was petechiae, ecchymosis & purpura in 33.8% cases. Among the thrombocytopenic pregnant women in our study, 60.8% had mild thrombocytopenia, 24.3% had moderate thrombocytopenia and 14.9% had severe thrombocytopenia
Conclusion: The study demonstrated that thrombocytopenia is a frequent finding in pregnancy. It has many potential causes but gestational thrombocytopenia (GT) predominates. Degree of thrombocytopenia was mild to moderate.
Keywords: Pregnancy, Thrombocytopenia, Petechiae, Ecchymosis