Open AccessA COMPARATIVE STUDY OF ASSESSMENT OF ROLE OF TRANEXAMIC ACID IN CONTROLLING BLOOD LOSS IN ORTHOPAEDIC SURGERIES: A RANDOMISED CONTROL TRIAL.
Author(s) -
Deepak Kumar,
Santosh Kumar
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i4.1180
Subject(s) - tranexamic acid , medicine , blood loss , placebo , saline , anesthesia , surgery , randomized controlled trial , orthopedic surgery , blood transfusion , alternative medicine , pathology
Aim: to study the role of Tranexamic Acid in Controlling Blood Loss In orthopaedic surgeries.
Material & Methods: 50 patients were included in the study during the study period. Patients were randomly allotted to 2 groups of equal participants. The first group (Group A) received Tranexamic Acid. The second group (Group B) was given Normal saline as placebo. The Total Blood Loss ( intra operative + post operative ) and Fall in Haemoglobin levels were measured post-operatively at 24 and 72 hrs of post-operative period.
Result: The group A had showed significantly reduced total blood loss and fall in Haemoglobin, thus, requiring fewer blood transfusions. No complications were observed.
Conclusions: the present investigation concluded that Tranexamic acid can be effective in reducing blood loss and subsequent fall in haemoglobin.
Keywords: Tranexamic acid, Bleeding, Major Orthopaedic surgeries.