Open AccessPREVALENCE OF BLOOD GROUP ANTIGENS OTHER THAN ABO-RhD IN HEALTHY BLOOD DONORS AT A TERTIARY CARE CENTER IN WESTERN RAJASTHAN, INDIA
Author(s) -
Ravindra Kumar Yadav,
Dev Raj Arya,
N.L. Mahawar,
Arun Bharti,
Shailendra Vashistha,
Sonam Alha,
Kaluram Meghwal
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i3.1028
Subject(s) - abo blood group system , medicine , antigen , rh blood group system , blood donor , population , tertiary care , single center , immunology , antibody , environmental health
It is important to know the frequencies of the various antigens to predict the availability of blood units for alloimmunized patients. Because of the fact that there is always a chance of diversity in phenotype pattern of a donor population, we decided to conduct a study on antigen phenotyping of regular blood donors.
Methodology: This blood bank based cross-sectional analytical study was carried out amongst 500 voluntary blood donors over a period of 8 months, i.e., from April, 2019 to November, 2019. Samples from all these donors were subjected to extended phenotyping (C, c, E, e, K, M, N, S, Jka, Jkb, Fya, Fyb, Lea and Leb).
Results: In present study, we observed the percentage frequencies of C, c, E, e, K, M, N, S, P1, Lea, Leb, Jka, Jkb, Fya and Fyb antigens as 75.6%, 53.2%, 18.4%, 97.75%, 3.8%, 82.4%, 58.4%, 43.8%, 66.2%, 16.8%, 52.6%, 80.0%, 67.6%, 79.4% and 54.6% respectively. Conclusion: Outcomes of such studies can be used to formulate a rare blood group donor registry and compatible blood can be provided to the patients (especially those requiring multiple transfusions).
Keywords: Antigens, Phenotyping, Blood donors.