Open AccessRELATIONSHIP BETWEEN ALZHEIMER’S DISEASE & PERIODONTITIS - A LITERATURE REVIEW
Author(s) -
K Nivetha,
Ayswarya V Vummidi,
Paavai Ilango,
T Abirami,
Arulpari Mahalingam,
Vineela Katam Reddy,
Angel Infant R,
A Meenambal
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i2.999
Subject(s) - periodontitis , porphyromonas gingivalis , disease , treponema denticola , inflammation , medicine , alzheimer's disease , immunology , pathology , dentistry
Periodontitis is the microbial infection often causing inflammation of the gingiva, bone loss and tooth mobility. Apart from periodontitis, periodontal bacteria like Porphyromonas gingivalis, Spirochetes, Treponema denticola are known to cause systemic diseases such as cardiovascular diseases, preterm low birth weight infants, Alzheimer’s diseases etc. Alzheimer’s disease is a progressive mental deterioration of the brain that can occur in middle or old aged individual due to generalized regeneration of neurons in the brain. Literature has shown that inflammation plays a vital role in the progression of Alzheimer’s disease where periodontitis is a risk factor proving the focal infection theory. This article reviews the relationship of periodontitis in Alzheimer’s disease and its role in modifying the disease.
Keywords: Alzheimer’s Disease, Chronic Periodontitis, Periomedicine, Inflammation