Open AccessA COMPARATIVE STUDY BETWEEN ETOMIDATE AND PROPOFOL AS AN INDUCTION AGENT DURING INDUCTION, LARYNGOSCOPY AND INTUBATION
Author(s) -
Supriya Agarwal,
Vidushi Sharma
Publication year - 2020
Publication title -
international journal of medical and biomedical studies
Language(s) - English
Resource type - Journals
eISSN - 2589-8698
pISSN - 2589-868X
DOI - 10.32553/ijmbs.v4i12.1601
Subject(s) - etomidate , propofol , medicine , anesthesia , intubation , laryngoscopy , incidence (geometry) , physics , optics
Background: The objective of study was to compare Etomidate and Propofol as induction agents and their effect on Pain on injection, time to loss of consciousness and myoclonic movements.
Methods: The study was carried out on 100 patients of ASA grade I and II between 18-58yrs of age of either sex enrolled for this prospective randomized double blind study, admitted in K D Medical College, Hospital & Research Center, Mathura (U.P) and scheduled for elective surgical procedures under general anaesthesia and endotracheal intubation.
Results: The incidence of pain on injection in propofol group was more as compared to etomidate group (p value <0.05). In propofol group 25(50%) patients while in etomidate group only 2(4%) patients had pain on injection. Etomidate group had significantly more myoclonic movements than propofol group (p value <0.05). In etomidate group 18(36%) patients had myoclonic movements of various severity, while in propofol group no patient had myoclonic movements.
Conclusion: Incidence of apnoea on induction was more in propofol group than etomidate group but comparison was not statistically significant.
Keywords: Apnea, Propofol, Etomidate.