Human Papilloma Virus: Biomolecular Aspect | Zendy

Patiyus Agustiansyah | Zendy; Rizal Sanif | Zendy; Siti Nurmaini | Zendy; Irfannuddin Irfannuddin | Zendy; Legiran | Zendy

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Human Papilloma Virus: Biomolecular Aspect

Author(s) -

Patiyus Agustiansyah,

Rizal Sanif,

Siti Nurmaini,

Irfannuddin Irfannuddin,

Legiran

Publication year - 2021

Publication title -

bioscientia medicina journal of biomedicine and translational research

Language(s) - English

Resource type - Journals

ISSN - 2598-0580

DOI - 10.32539/bsm.v5i3.327

Subject(s) - genotyping , human papilloma virus , virus , virology , cervical cancer , cytology , genotype , liquid based cytology , medicine , cancer , biology , pathology , gene , genetics

HPV is a sexually transmitted virus, and high-risk HPV DNA was found in 99.7%of cervical cancer specimens. Within 12 to 24 months of exposure to the virus,90% of HPV infections disappear or become inactive. However, infection with high-risk strains of HPV persist which then increases the risk of progression to cervicalcancer. The detection of precancerous lesions consists of various methods,including pap smear (conventional or liquid-base cytology / LBC), visualinspection of acetic acid (IVA), visual inspection of lugoliodine (VILI), and HPV DNAtest (genotyping / hybrid capture).

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