Open AccessHuman Papilloma Virus: Biomolecular Aspect
Author(s) -
Patiyus Agustiansyah,
Rizal Sanif,
Siti Nurmaini,
Irfannuddin Irfannuddin,
Legiran
Publication year - 2021
Publication title -
bioscientia medicina
Language(s) - English
Resource type - Journals
ISSN - 2598-0580
DOI - 10.32539/bsm.v5i3.327
Subject(s) - genotyping , human papilloma virus , virus , virology , cervical cancer , cytology , genotype , liquid based cytology , medicine , cancer , biology , pathology , gene , genetics
HPV is a sexually transmitted virus, and high-risk HPV DNA was found in 99.7%of cervical cancer specimens. Within 12 to 24 months of exposure to the virus,90% of HPV infections disappear or become inactive. However, infection with high-risk strains of HPV persist which then increases the risk of progression to cervicalcancer. The detection of precancerous lesions consists of various methods,including pap smear (conventional or liquid-base cytology / LBC), visualinspection of acetic acid (IVA), visual inspection of lugoliodine (VILI), and HPV DNAtest (genotyping / hybrid capture).