Open AccessChemical constituents of the propolis from the stingless bee Trigona minor
Author(s) -
Hai Xuan Nguyen,
Mai Thi Thanh Nguyen,
Nhan Trung Nguyen
Publication year - 2019
Publication title -
khoa học và công nghệ: tự nhiên
Language(s) - English
Resource type - Journals
ISSN - 2588-106X
DOI - 10.32508/stdjns.v2i5.778
Subject(s) - propolis , stingless bee , lignan , natural product , botany , chemistry , traditional medicine , biology , apidae , organic chemistry , hymenoptera , medicine
Propolis is a natural product produced by bees, and it is a mixture of resins and other bee excretions. The chemical composition of each type of propolis and its associated bioactivities also depend on the geographical regions, its food and the bee species. In Vietnam, propolis has been used in traditional medicine as the remedy to improve health and prevent diseases. From the ethanolic extract of the stingless bee propolis Trigona minor (Meliponini, Apidae), four lignan compounds were isolated. Their chemical structures were determined as (+)-isolariciresinol (1), 5-methoxy-(+)- isolariciresinol (2), (+)-lyoniresinol (3), and 6-(4- hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo[3.3.0] octan-2-one (4) by spectroscopic methods as well as comparing with data in the literature. Among them, compound 4 was the first isolated from natural sources, while others were isolated for the first time from this stingless bee propolis.