Open AccessMulti-component reaction between aromatic aldehyde, ethyl acetoacetate and urea catalyzed by Brönsted ionic liquid under microwave irradiation
Author(s) -
Hai Truong Nguyen,
Nguyen Thi Thanh Huynh,
Phuong Hoang Tran
Publication year - 2019
Publication title -
khoa học và công nghệ: tự nhiên
Language(s) - English
Resource type - Journals
ISSN - 2588-106X
DOI - 10.32508/stdjns.v2i3.755
Subject(s) - ionic liquid , catalysis , ethyl acetoacetate , aldehyde , chemistry , mass spectrometry , electrospray ionization , electrospray , nuclear chemistry , inorganic chemistry , organic chemistry , chromatography
[(SO3H)4C4C1Im]HSO4 is a Brönsted ionic liquid, which was found to be an effective catalyst for organic synthesis. Ionic liquid was prepared from 1-methylimidazole and 1,4- butanesultone (ratio = 1:1), structure of [(SO3H)4C4C1Im]HSO4 was characterized by using nuclear magnetic resonance NMR spectroscopy and high-resolution electrospray ionisation mass spectrometry (HR-ESI-MS). Ionic liquid was used as a catalyst for multi-component reaction, which afforded the desired products in high yields (over 80%) and short reaction time (5 min) under microwave irradiation. The catalyst could be recycled several times without loss of efficient catalytic activity.