STUDY ON PREPARATION OF CHITOSAN NANOPARTICLE AS PROTEIN DELIVERY CARRIER FOR DRUG DELIVERY APPLICATION | Zendy

Tuyet Thi Anh Duong | Zendy; Khương Quoc Võ | Zendy; Phuong Hue Phan | Zendy; Phong Nguyen | Zendy

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STUDY ON PREPARATION OF CHITOSAN NANOPARTICLE AS PROTEIN DELIVERY CARRIER FOR DRUG DELIVERY APPLICATION

Author(s) -

Tuyet Thi Anh Duong,

Khương Quoc Võ,

Phuong Hue Phan,

Phong Nguyen

Publication year - 2011

Publication title -

science and technology development journal

Language(s) - English

Resource type - Journals

ISSN - 1859-0128

DOI - 10.32508/stdj.v14i4.2048

Subject(s) - chitosan , nanoparticle , drug delivery , chemical engineering , drug carrier , materials science , nuclear chemistry , chemistry , nanotechnology , organic chemistry , engineering

This work investigates the polyanion initiated gelation process in fabricating chitosan (CS)-tripolyphosphate (TPP) nanoparticle intended to be used as protein delivery carrier. Variations in cross-linking agents, CS/TPP weight ratio and solution pH were investigated. The chitosan nanoparticles were characterized by several analytical techniques such as FT-IR, XRD, FE_SEM and TEM. Finally, protein loading efficiency (LE) and protein loading capacity (LC) were investigated.

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