Open AccessQuercetin as a precursor in the synthesis of analogues of fulvic acids and their antibacterial properties
Author(s) -
Валентина А. Литвин,
Roger Abi Njoh
Publication year - 2021
Publication title -
voprosy himii i himičeskoj tehnologii/voprosy himii i himičeskoj tehnologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.278
H-Index - 7
eISSN - 2413-7987
pISSN - 0321-4095
DOI - 10.32434/0321-4095-2021-135-2-56-64
Subject(s) - chemistry , fulvic acid , quercetin , natural product , redox , humic acid , antibacterial activity , organic chemistry , nuclear chemistry , antioxidant , bacteria , fertilizer , biology , genetics
A simple, fast and effective method for producing synthetic substances with properties similar to natural humic substances has been proposed. The synthesis method is based on the oxidation of quercetin by molecular oxygen in an alkaline medium, followed by conversion to the acid form by passing through a cation exchange column. Study of elemental and functional compositions, spectral properties (UV/Vis and IR range) and redox characteristics allowed qualifying the resulting product as a synthetic fulvic acid. The enhanced antibacterial properties of the obtained synthetic product were established. The minimum concentration of inhibition of synthetic fulvic acid derived from quercetin is 25 g mL–1, which is in 100 times less than for natural humic substances.