Open AccessEvaluation of shampoo with chlorhexidine 4 % efficacy at the secondary microbial infections in dogs with chronical alle
Author(s) -
Лидия Куприянова,
Lidiya Kupriyanova,
Евгения Багринцева,
Evgeniya Bagrinceva,
О В Петрова,
О В Петрова
Publication year - 2019
Publication title -
rossijskij veterinarnyj žurnal
Language(s) - English
Resource type - Journals
ISSN - 2500-4379
DOI - 10.32416/article_5c8faff76c7474.08953074
Subject(s) - shampoo , chlorhexidine , medicine , erythema , antimicrobial , dermatology , pyoderma , clinical efficacy , antibiotics , dentistry , surgery , microbiology and biotechnology , pathology , biology
In overcoming of antibiotic resistance in patients with chronic pruritic dermatoses, which often need lifelong monitoring and anti-inflammatory and antimicrobial therapy, topical using of shampoo with chlorhexidine 4% might be the optimal solution. Aim of research. To study the clinical efficacy of shampoo with chlorhexidine 4% (API-SAN, Russia) in dogs with chronic allergic dermatosis and secondary microbial diseases. Materials and methods. Experimental groups were formed: dogs with superficial pyoderma (1st), microbial pododermatitis (2nd) and malassesia dermatitis (3rd), as well as the control group. Results. In this study, we noticed that the pedigree and age sensitivity to dermatological problems was absent. The usual type of dog nutrition was not clearly correlated with the frequency of contacting with dermatologist. The result of the study was taken into account after the 14-day course of treatment in animals with an antimicrobial shampoo with 4 % chlorhexidine and was based in a decrease in the inflammatory (pruritus, skin erythema, exudation), reduction of lesions during planimetric measurement and detection of persistent restorative dynamics of the skin and hair. It was found that against the use of antimicrobial shampoo resistant clinical remission was observed within 7 days in the experimental groups and for 9-9.5 days in the control group. The clinical efficacy of anti-microbial shampoo with 4% chlorhexidine was shown by the results of negative сytology in the most of animals in the experimental groups.