Open AccessFood as a source of exposure to nickel
Author(s) -
Monika Mania,
Małgorzata Rebeniak,
Jacek Postupolski
Publication year - 2019
Publication title -
roczniki państwowego zakładu higieny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 19
eISSN - 2451-2311
pISSN - 0035-7715
DOI - 10.32394/rpzh.2019.0090
Subject(s) - european commission , environmental health , tolerable daily intake , population , food safety , food contact materials , body weight , toxicology , food intake , european union , acceptable daily intake , risk assessment , medicine , business , food science , food packaging , biology , computer security , computer science , pesticide , agronomy , economic policy
According to the European Food Safety Authority (EFSA), food is the main source of nickel intake by the general population. Based on the risk assessment, EFSA determined the tolerable daily intake of this element (TDI) from all sources at the level of 2.8 μg/kg body weight, which is for an adult 196 μg, while for a child 56 μg. The Benchmark Dose Lower Confidence Limit (BMDL10) associated with dermatitis at 1.1 μg/kg body weight was also determined as well as the Margin of Exposure (MOE). Nickel intake in the Member States varies and depends on consumption habits. CONTAM Panel of EFSA considered the unlikely possibility of developing cancers related to the intake of nickel with food. According to experts, other harmful effects on the human body are more often identified. An additional aspect requiring further investigations that will allow an actual estimation of exposure associated with intake of this element by various groups of population is the issue of nickel absorption in the human body. The review of the EFSA opinion on the request of the European Commission planned in the near future based on the collected data as part of the action of the Commission Recommendation (EU) 2016/1111 on monitoring the presence of nickel in food will contribute to taking appropriate actions related to consumer protection, including the most vulnerable groups of population.