
Pilonidal Sinus Carcinoma dying from Squamous Cell Carcinoma within 14 months after Diagnosis.
Author(s) -
Marius Dettmer,
Marcel Bonni,
Konstantinos Degiannis,
Matthias Maak,
Dietrich Doll,
Igors Iesalnieks
Publication year - 2022
Publication title -
albanian journal of trauma and emergency surgery
Language(s) - English
Resource type - Journals
eISSN - 2616-4922
pISSN - 2521-8778
DOI - 10.32391/ajtes.v6i1.255
Subject(s) - medicine , biopsy , sinus (botany) , radiation therapy , carcinoma , basal cell , incidence (geometry) , coccyx , surgery , radiology , pathology , botany , physics , optics , biology , genus , sacrum
The incidence of Pilonidal Sinus Disease (PSD) is increasing worldwide, especially in the developing and developed countries. As long-standing chronic infection may trigger neoplastic transformation, more carcinoma arising from PSD are to be expected with an incidence of 0,1%.
Methods: Case report describing a Squamous cell carcinoma (SCC) arising from PSD
Results: A 60-year-old male presented with a 6cm x 10cm ulcerating wound in the sacrococcygeal area, which was painful for 3 months. A biopsy initially revealed a highly differentiated squamous cell carcinoma (cT3cN1acM0G1). Soft tissue MRI showed possible infiltration of the coccyx, and a staging CT showed suspicious enlarged lymph nodes within both inguinal regions. The patient underwent a full 20x1,8 Gy chemoradiation with partial response of the primary. Surgical Resection was recommended. The patient did not show up for follow-up after chemoradiation and refused further treatment. He demised after 14 months due to pulmonary metastases.
Conclusion: Even a curative intended chemoradiation of this highly differentiated tumour led to a dismal outcome of disease after 14 months. Cases of PSD carcinomas often present as atypical cutaneous SCC.