Open AccessANTIBACTERIAL ACTIVITY OF MIANA LEAF ESTRACT (Coleus atropurpereus) ON Steptococcus aureus
Author(s) -
Anita Anita,
Mujahidah Basarang,
Rahmawati Rahmawati
Publication year - 2020
Publication title -
media kesehatan politeknik kesehatan makassar/media kesehatan politeknik kesehatan makassar
Language(s) - English
Resource type - Journals
eISSN - 2549-0567
pISSN - 1907-8153
DOI - 10.32382/medkes.v15i1.1033
Subject(s) - coleus , positive control , antibacterial activity , agar , agar diffusion test , chemistry , saponin , flavonoid , negative control , traditional medicine , bacterial growth , bacteria , horticulture , biology , biochemistry , medicine , antioxidant , genetics , alternative medicine , pathology
Miana leaf(Coleus atrropurpureus) is the one of biofarmacology plant which using for antibacterial activity.Miana leaf contains flavonoid, tanin, saponin which can inhibit growth of bacteria. The aims this research were study antibacterial activity of miana leaf extract on Streptococcus aureus.This research used laboratory observation method which used miana leaf extract concentration 250 mg/ml, 125 mg/ml, 62.5 mg/ml, 31,25 mg/ml, and 15,625 mg/ml. This research used tetracylin for positive control and aquadest for negative control which growth 0n 37o C used difusion agar method. The results showed antibactrila activity miana leaf extract with a concentration 250 mg/ml with inhibition zone 0.00 mm, 125 mg/ml with inhibition zone 0,00 mm, 62,5 mg/ml with inhibition zone 0,00 mm, 31,25 mg/ml with inhibition zone 0,00 mm, and 15,62 mg/ml with inhibition zone 0,00 mm. For positive control showed inhibition zone 27,6 mm and negative control with inhibition zone 0,00 mm. Miana leaf extract concentration 250 mg/ml, 125 mg/ml, 62,5 mg/ml, 31,25 mg/ml and 15,62 mg/ml were not effectively inhibit Streptococcus sp.