Open AccessPupillometric Monitoring of Nociception in Cardiac Anesthesia: A Randomized Controlled Study
Author(s) -
Felix Bartholmes,
Nathalie M. Malewicz,
Melanie Ebel,
Peter Zahn,
Christine H. MeyerFrießem
Publication year - 2020
Publication title -
deutsches ärzteblatt international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.436
H-Index - 60
ISSN - 1866-0452
DOI - 10.3238/arztebl.2020.0833
Subject(s) - sufentanil , medicine , anesthesia , pupillometry , nociception , randomized controlled trial , opioid , confidence interval , surgery , pupil , receptor , neuroscience , biology
High-dose opioids are conventionally used for cardiac anesthesia, but without monitoring of nociception. In non-cardiac surgical procedures the intra - operative dose of opioids can be individualized and reduced with pupillometric monitoring of the pupillary pain index (PPI; scale 1-9). A randomized controlled trial was carried out to explore whether pupillometry can be used for nociception monitoring in cardiac anesthesia and whether it leads to opioid reduction.