Microbial Transformation of Some Ethylpyridines by Fungi | Zendy

Igor A. Parshikov | Zendy

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Microbial Transformation of Some Ethylpyridines by Fungi

Author(s) -

Igor A. Parshikov

Publication year - 2022

Language(s) - English

Resource type - Reports

DOI - 10.32370/iaj.2635

Subject(s) - hydroxylation , pyridine , chemistry , biotransformation , ring (chemistry) , methylene , fungus , nitrogen atom , transformation (genetics) , stereoselectivity , nitrogen , medicinal chemistry , organic chemistry , beauveria bassiana , methyl group , stereochemistry , biochemistry , group (periodic table) , botany , enzyme , biology , gene , catalysis , biological pest control

We were observed transformation 4-ethylpyridine and 2-methyl-5-ethylpyridine by fungus Beauveria bassiana ATCC 7159. Stereoselective oxidation of methylene group leading to the optically active (-)-(1-hydroxyethyl)pyridine was shown. Besides, the hydroxylation of methyl groups and the oxidation of the heterocyclic ring in the nitrogen atom to the respective primary alcohols and N-oxides were observed

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