
EXPERT STUDY OF TRICYCLIC ANTIDEPRESSANTS
Author(s) -
M. V. Zarubina,
Irina Sych,
Irina Sych
Publication year - 2016
Publication title -
teorìâ ta praktika sudovoï ekspertizi ì krimìnalìstiki
Language(s) - English
Resource type - Journals
eISSN - 2708-5171
pISSN - 1993-0917
DOI - 10.32353/khrife.2016.33
Subject(s) - doxepin , tricyclic , amitriptyline , imipramine , clomipramine , tianeptine , chromatography , chemistry , desipramine , pharmacology , medicine , antidepressant , alternative medicine , pathology , hippocampus
Consideration is given to the methods of examining the tricyclic antidepressants (tianeptine, amitriptyline, imipramine, doxepin, clomipramine). We selected the most sensitive reagents allowing to differentiate and identify these medicines; carried out their examinations by thin-layer chromatography; selected the organic solvent systems and obtained chromatographic characteristics. The IR spectroscopy method was used to determine the main absorption bands typical for medicinal substances under examination.