Open AccessKI-67 AS A PROGNOSTIC FACTOR OF MYELODYSPLASTIC SYNDROME
Author(s) -
Г. С. Стародуб,
N. V. Goryainova,
Т. П. Перехрестенко,
О. В. Басова,
Nataliia Tretiak,
А. І. Гордієнко
Publication year - 2016
Publication title -
ukraïnsʹkij naukovo-medičnij molodìžnij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2311-6951
pISSN - 1996-353X
DOI - 10.32345/usmyj.2(95)().2016.5-8
Subject(s) - haematopoiesis , bone marrow , peripheral blood , myelodysplastic syndromes , medicine , myeloid , chemotherapy , induction chemotherapy , oncology , immunology , cancer research , biology , stem cell , genetics
Patients with MDS RAEB II were examined. The decrease in dynamics of intracellular K³-67 protein expression was determined in patients with MDS RAEB II with positive response to chemotherapy, and the increase in proliferative activity of haematopoietic cells of peripheral blood (PB) and bone marrow (BM) was determined in patients with MDS RAEB II in transformation and acute myeloid leukaemia (AML) after MDS.