Open AccessMoebius syndrome with baroreflex failure in an adolescent female
Author(s) -
Megan Bowers,
Gabrielle Goldvon Simson
Publication year - 2015
Publication title -
journal of pediatric genetics
Language(s) - English
Resource type - Journals
eISSN - 2146-4596
pISSN - 2146-460X
DOI - 10.3233/pge-2012-031
Subject(s) - baroreflex , dysautonomia , medicine , orthostatic vital signs , etiology , orthostatic intolerance , familial dysautonomia , anesthesia , pediatrics , blood pressure , heart rate , disease
An adolescent female with Moebius syndrome developed paroxysmal hypertension, orthostatic hypotension and autonomic symptoms. Common causes of dysautonomia were excluded by the work-up, which supported a diagnosis of baroreflex failure. Neurological testing suggested dysfunction of the tenth cranial nerve as the etiology. This report suggests that baroreflex dysfunction should be considered in Moebius syndrome patients displaying autonomic symptoms.