z-logo
open-access-imgOpen Access
Patterns of balance loss with systematic perturbations in Parkinson’s disease and multiple sclerosis
Author(s) -
Diane D. Allen,
Jessica Gadayan,
Rebecca Hughes,
Christine Magdalin,
Catherine Jang,
Amy Schultz,
Kathryn F. Scott,
Leah Vivero,
Rolando L Lazaro,
Gail L. Widener
Publication year - 2021
Publication title -
neurorehabilitation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.611
H-Index - 65
eISSN - 1878-6448
pISSN - 1053-8135
DOI - 10.3233/nre-210200
Subject(s) - multiple sclerosis , balance (ability) , medicine , parkinson's disease , analysis of variance , rating scale , physical medicine and rehabilitation , disease , psychology , developmental psychology , psychiatry
BACKGROUND: Multiple sclerosis (MS) and Parkinson’s disease (PD) may affect balance differently. However, no studies have compared loss of balance (LOB) patterns following multi-directional perturbations. OBJECTIVE: 1) determine reliability of LOB ratings following standardized manual perturbations; 2) compare LOB ratings in MS, PD, and healthy control (HC) groups following perturbations at upper/lower torso, in anterior/posterior, right/left, and rotational directions. METHODS: 1) reviewers rated videotaped LOB following perturbations applied by 4 clinicians in 6–10 HCs. 2) three groups (64 MS, 42 PD and 32 HC) received perturbations. LOB ratings following perturbations were analyzed using two-factor mixed ANOVAs for magnitude and prevalence. RESULTS: 1) LOB ratings showed moderate to good ICC and good to excellent agreement. 2) MS group showed greater magnitude and prevalence of LOB than PD or HC groups (p < .001). All groups showed greater LOB from right/left versus anterior/posterior perturbations (p < .01). PD showed greater LOB from perturbations at upper versus lower torso; MS and HC showed greater LOB from posterior versus anterior perturbations. CONCLUSIONS: Our reliable rating scale showed differences in patterns of LOB following manual perturbations in MS, PD, and HC. Clinically accessible and reliable assessment of LOB could facilitate targeted perturbation-based interventions and reduce falls in vulnerable populations.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here