Open AccessClinical and vital sign changes associated with late-onset sepsis in very low birth weight infants at 3 NICUs
Author(s) -
Brynne A. Sullivan,
VP Nagraj,
Katie L. Berry,
Noa Fleiss,
Ami Rambhia,
Rupin Kumar,
Aaron Wallman-Stokes,
Zachary Vesoulis,
Rakesh Sahni,
Sarah J. Ratcliffe,
Douglas E. Lake,
J. Randall Moorman,
Karen D. Fairchild
Publication year - 2021
Publication title -
journal of neonatal-perinatal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.444
H-Index - 17
eISSN - 1934-5798
pISSN - 1878-4429
DOI - 10.3233/npm-200578
Subject(s) - medicine , vital signs , lethargy , sepsis , tachypnea , pediatrics , intensive care , anesthesia , intensive care medicine , tachycardia
In premature infants, clinical changes frequently occur due to sepsis or non-infectious conditions, and distinguishing between these is challenging. Baseline risk factors, vital signs, and clinical signs guide decisions to culture and start antibiotics. We sought to compare heart rate (HR) and oxygenation (SpO2) patterns as well as baseline variables and clinical signs prompting sepsis work-ups ultimately determined to be late-onset sepsis (LOS) and sepsis ruled out (SRO).