SETD2 Regulates the Methylation of Translation Elongation Factor eEF1A1 in Clear Cell Renal Cell Carcinoma1 | Zendy

Robert Hapke | Zendy; Lindsay Venton | Zendy; Kristie L. Rose | Zendy; Quanhu Sheng | Zendy; Anupama Reddy | Zendy; Rebecca M. Prather | Zendy; Angela Jones | Zendy; W. Kimryn Rathmell | Zendy; Scott M. Haake | Zendy

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SETD2 Regulates the Methylation of Translation Elongation Factor eEF1A1 in Clear Cell Renal Cell Carcinoma1

Author(s) -

Robert Hapke,

Lindsay Venton,

Kristie L. Rose,

Quanhu Sheng,

Anupama Reddy,

Rebecca M. Prather,

Angela Jones,

W. Kimryn Rathmell,

Scott M. Haake

Publication year - 2022

Publication title -

kidney cancer

Language(s) - English

Resource type - Journals

eISSN - 2468-4570

pISSN - 2468-4562

DOI - 10.3233/kca-220009

Subject(s) - histone methyltransferase , histone h3 , methylation , histone , biology , eukaryotic translation elongation factor 1 alpha 1 , translation (biology) , microbiology and biotechnology , methyltransferase , histone methylation , gene expression , cancer research , dna methylation , gene , genetics , rna , messenger rna , ribosome

SET domain-containing protein 2 ( SETD2 ) is commonly mutated in renal cell carcinoma. SETD2 methylates histone H3 as well as a growing list of non-histone proteins.

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