Open AccessChoroidal Thickness Correlates with Clinical and Imaging Metrics of Parkinson’s Disease: A Pilot Study
Author(s) -
Gregory L. Brown,
Mona Lotfipour Camacci,
Sean D Kim,
Stephanie L. Grillo,
James Nguyen,
Douglas A Brown,
Sarah P Ullah,
Mechelle M. Lewis,
Guangwei Du,
Lan Kong,
Jeffrey M. Sundstrom,
Xuemei Huang,
Esther M Bowie
Publication year - 2021
Publication title -
journal of parkinson's disease/journal of parkinson's disease (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.747
H-Index - 45
eISSN - 1877-718X
pISSN - 1877-7171
DOI - 10.3233/jpd-212676
Subject(s) - pars compacta , substantia nigra , parkinson's disease , medicine , rem sleep behavior disorder , biomarker , ophthalmology , pathology , disease , chemistry , biochemistry
Parkinson's disease (PD) is marked clinically by motor symptoms and pathologically by Lewy bodies and dopamine neuron loss in the substantia nigra pars compacta (SNc). Higher iron accumulation, assessed by susceptibility MRI, also is observed as PD progresses. Recently, evidence has suggested that PD affects the retina.