A European Observational Study to Evaluate the Safety and the Effectiveness of Safinamide in Routine Clinical Practice: The SYNAPSES Trial1
Author(s) -
Giovanni Abbruzzese,
Jaime Kulisevsky,
Bruno Bergmans,
Juan Carlos GómezEsteban,
Georg Kägi,
Jason Raw,
Ambra Stefani,
Tobias Warnecke,
Wolfgang H. Jost
Publication year - 2020
Publication title -
journal of parkinson s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.747
H-Index - 45
eISSN - 1877-718X
pISSN - 1877-7171
DOI - 10.3233/jpd-202224
Subject(s) - medicine , adverse effect , observational study , parkinson's disease , cohort , cohort study , retrospective cohort study , pediatrics , disease
Safinamide modulates both dopaminergic and glutamatergic systems with positive effects on motor and non-motor symptoms of Parkinson's disease (PD). The drug utilization study SYNAPSES was designed to investigate the use of safinamide in routine clinical practice, as recommended by the European Medicines Agency.
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