Open AccessPharmacotherapy Use for Non-Motor Symptoms Among de novo Parkinson’s Disease Parkinson’s Progression Markers Initiative Participants
Author(s) -
Monica Javidnia,
Ira Shoulson,
Karl Kieburtz,
Charles Venuto
Publication year - 2020
Publication title -
journal of parkinson's disease/journal of parkinson's disease (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.747
H-Index - 45
eISSN - 1877-718X
pISSN - 1877-7171
DOI - 10.3233/jpd-201973
Subject(s) - parkinson's disease , depression (economics) , medicine , motor symptoms , disease , anxiety , constipation , psychiatry , physical therapy , economics , macroeconomics
Parkinson's disease (PD) patients experience a range of non-motor symptoms that are believed to be related to disease pathophysiology, many of which are treatable by medications. Among newly-diagnosed PD participants in the Parkinson's Progression Markers Initiative study, we describe (1) the frequency of medication use for common non-motor symptoms, and (2) when non-motor symptomatic treatment was initiated relative to PD diagnosis. Non-motor medication use was reported by 73% of participants, most commonly for depression, constipation, and anxiety. Treatment of some non-motor symptoms, notably depression, antedated diagnosis. These data may be useful for studies of non-motor symptoms in PD.