Open AccessImproved Executive Function and Callosal White Matter Microstructure after Rhythm Exercise in Huntington's Disease
Author(s) -
Claudia MetzlerBaddeley,
Jaime Cantera,
Elizabeth Coulthard,
Anne Elizabeth Rosser,
Derek K. Jones,
Roland Baddeley
Publication year - 2014
Publication title -
journal of huntington's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.081
H-Index - 24
eISSN - 1879-6400
pISSN - 1879-6397
DOI - 10.3233/jhd-140113
Subject(s) - corpus callosum , white matter , psychology , executive dysfunction , neuroscience , basal ganglia , executive functions , grey matter , cognition , medicine , physical medicine and rehabilitation , audiology , magnetic resonance imaging , central nervous system , radiology , neuropsychology
Huntington's disease (HD) is an autosominal dominant neurodegenerative condition that leads to progressive loss of motor and cognitive functions. Early symptoms in HD include subtle executive dysfunction related to white and grey matter loss in cortico-striatal-thalamic loops. There is no cure for HD and hence a significant need for early intervention with the potential to delay the clinical onset of the disease.