Open AccessA Novel Inhibitor Targeting NLRP3 Inflammasome Reduces Neuropathology and Improves Cognitive Function in Alzheimer’s Disease Transgenic Mice
Author(s) -
Ram Kuwar,
Andrew Rolfe,
Long Di,
Hallie Blevins,
Yiming Xu,
Xuehan Sun,
George S. Bloom,
Shijun Zhang,
Dong Sun
Publication year - 2021
Publication title -
journal of alzheimer s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-210400
Subject(s) - inflammasome , neuroinflammation , pyrin domain , neuroscience , genetically modified mouse , synaptic plasticity , neurogenesis , biology , transgene , neuroprotection , amyloid precursor protein , alzheimer's disease , medicine , microbiology and biotechnology , receptor , immunology , disease , inflammation , genetics , gene
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