Open AccessFour Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies
Author(s) -
Shama Karanth,
Frederick A. Schmitt,
Peter T. Nelson,
Yuriko Katsumata,
Richard J. Kryscio,
David W. Fardo,
Jordan P. Harp,
Erin L. Abner
Publication year - 2021
Publication title -
journal of alzheimer's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-210293
Subject(s) - cognition , dementia , neuropathology , psychology , cognitive decline , cohort , gerontology , multinomial logistic regression , disease , medicine , neuroscience , pathology , statistics , mathematics
Late-life cognitive function is heterogeneous, ranging from no decline to severe dementia. Prior studies of cognitive trajectories have tended to focus on a single measure of global cognition or individual tests scores, rather than considering longitudinal performance on multiple tests simultaneously.