Open AccessElevated Inflammatory Markers and Arterial Stiffening Exacerbate Tau but Not Amyloid Pathology in Older Adults with Mild Cognitive Impairment
Author(s) -
Alexandra L. Clark,
Alexandra J. Weigand,
Kelsey R. Thomas,
Seraphina K. Solders,
Lisa DelanoWood,
Mark W. Bondi,
Rachel A. Bernier,
Erin E. Sundermann,
Sarah J. Banks,
Katherine J. Bangen
Publication year - 2021
Publication title -
journal of alzheimer's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-201382
Subject(s) - inflammation , apolipoprotein e , medicine , cognitive decline , cerebrospinal fluid , neurology , psychology , pathology , endocrinology , gastroenterology , disease , neuroscience , dementia
Age-related cerebrovascular and neuroinflammatory processes have been independently identified as key mechanisms of Alzheimer's disease (AD), although their interactive effects have yet to be fully examined.