APOE E2/E2 Is Associated with Slower Rate of Cognitive Decline with Age
Author(s) -
Benjamin Sweigart,
Stacy L. Andersen,
Anastasia Gurinovich,
Stephanie Cosentino,
Nicole Schupf,
Thomas T. Perls,
Paola Sebastiani
Publication year - 2021
Publication title -
journal of alzheimer s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-201205
Subject(s) - apolipoprotein e , genotype , cognitive decline , longitudinal study , confounding , cognition , allele , demography , tics , psychology , gerontology , medicine , biology , genetics , dementia , psychiatry , disease , gene , pathology , sociology
The E4 allele of the APOE gene is known to be associated with cognitive impairment. However, a limited number of studies have examined the association between the E2 allele and longitudinal changes of cognitive function.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom