Open AccessHerpes Labialis, Chlamydophila pneumoniae, Helicobacter pylori, and Cytomegalovirus Infections and Risk of Dementia: The Framingham Heart Study
Author(s) -
Eduardo Marques Zilli,
Adrienne O’Donnell,
Joel Salinas,
Hugo J. Aparicio,
Mitzi M. Gonzales,
Mini E. Jacob,
Alexa S. Beiser,
Sudha Seshadri
Publication year - 2021
Publication title -
journal of alzheimer's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-200957
Subject(s) - dementia , medicine , helicobacter pylori , cohort , incidence (geometry) , immunology , disease , physics , optics
An association between chronic infectious diseases and development of dementia has been suspected for decades, based on the finding of pathogens in postmortem brain tissue and on serological evidence. However, questions remain regarding confounders, reverse causality, and how accurate, reproducible and generalizable those findings are.