Automated Hippocampal Subfield Volumetric Analyses in Atypical Alzheimer’s Disease | Zendy

Musa Gabere | Zendy; Nha Trang Thu Pham | Zendy; Jonathan GraffRadford | Zendy; Mary M. Machulda | Zendy; Joseph R. Duffy | Zendy; Keith A. Josephs | Zendy; Jennifer L. Whitwell | Zendy

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Automated Hippocampal Subfield Volumetric Analyses in Atypical Alzheimer’s Disease

Author(s) -

Musa Gabere,

Nha Trang Thu Pham,

Jonathan GraffRadford,

Mary M. Machulda,

Joseph R. Duffy,

Keith A. Josephs,

Jennifer L. Whitwell

Publication year - 2020

Publication title -

journal of alzheimer s disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.677

H-Index - 139

eISSN - 1875-8908

pISSN - 1387-2877

DOI - 10.3233/jad-200625

Subject(s) - hippocampal formation , neuroscience , alzheimer's disease , disease , psychology , medicine

Posterior cortical atrophy (PCA) and logopenic progressive aphasia (LPA) are two of the most common variants of atypical Alzheimer's disease (AD). Both PCA and LPA are associated with relative sparing of hippocampus compared to neocortex, although hippocampal atrophy is observed. It is unclear whether regional patterns of hippocampal subfield involvement differ between PCA and LPA, and whether they differ from typical AD.

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