Microbleeds and Medial Temporal Atrophy Determine Cognitive Trajectories in Normal Aging: A Longitudinal PET-MRI Study
Author(s) -
MarieLouise Montandon,
François R. Herrmann,
Valentina Garibotto,
Cristelle Rodriguez,
Sven Haller,
Pantèleimon Giannakopoulos
Publication year - 2020
Publication title -
journal of alzheimer s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-200559
Subject(s) - hyperintensity , cognition , neuropsychology , medicine , magnetic resonance imaging , atrophy , effects of sleep deprivation on cognitive performance , psychology , cognitive decline , neuroimaging , cardiology , multivariate statistics , audiology , longitudinal study , pathology , neuroscience , radiology , dementia , disease , statistics , mathematics
The cognitive trajectories in normal aging may be affected by medial temporal atrophy (MTA) and amyloid burden, as well as vascular pathologies such as cortical microbleeds (CMB) and white matter hyperintensities (WMH).
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