Regional Hypoperfusion Predicts Decline in Everyday Functioning at Three-Year Follow-Up in Older Adults without Dementia | Zendy

Danielle L. Sanchez | Zendy; Kelsey R. Thomas | Zendy; Emily C. Edmonds | Zendy; Mark W. Bondi | Zendy; Katherine J. Bangen | Zendy

Open Access

Regional Hypoperfusion Predicts Decline in Everyday Functioning at Three-Year Follow-Up in Older Adults without Dementia

Author(s) -

Danielle L. Sanchez,

Kelsey R. Thomas,

Emily C. Edmonds,

Mark W. Bondi,

Katherine J. Bangen

Publication year - 2020

Publication title -

journal of alzheimer s disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.677

H-Index - 139

eISSN - 1875-8908

pISSN - 1387-2877

DOI - 10.3233/jad-200490

Subject(s) - dementia , cerebral hypoperfusion , gerontology , psychology , medicine , perfusion , disease

Increasing evidence indicates that cerebrovascular dysfunction may precede cognitive decline in aging and Alzheimer's disease (AD). Reduced cerebral blood flow (CBF) is associated with cognitive impairment in older adults. However, less is known regarding the association between CBF and functional decline, and whether CBF predicts functional decline beyond cerebrovascular and metabolic risk factors.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research