Open AccessTraffic-Related Air Pollution and Incident Dementia: Direct and Indirect Pathways Through Metabolic Dysfunction
Author(s) -
Kimberly C. Paul,
Mary N. Haan,
Yu Yu,
Kosuke Inoue,
Elizabeth Rose Mayeda,
Kristina Dang,
Jun Wu,
Michael Jerrett,
Beate Ritz
Publication year - 2020
Publication title -
journal of alzheimer's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-200320
Subject(s) - dementia , medicine , nox , air pollution , mediation , diabetes mellitus , environmental health , chemistry , endocrinology , disease , organic chemistry , political science , law , combustion
Ambient air pollution exposure has been associated with dementia. Additionally, epidemiologic evidence supports associations between air pollution and diabetes as well as diabetes and dementia. Thus, an indirect pathway between air pollution and dementia may exist through metabolic dysfunction.