Open AccessCerebral Amyloid Angiopathy and Neuritic Plaque Pathology Correlate with Cognitive Decline in Elderly Non-Demented Individuals
Author(s) -
Michael Malek-Ahmadi,
Kewei Chen,
Sylvia E. Perez,
Elliott J. Mufson
Publication year - 2019
Publication title -
journal of alzheimer's disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-180765
Subject(s) - cerebral amyloid angiopathy , senile plaques , amyloid (mycology) , pathology , medicine , cognitive decline , angiopathy , alzheimer's disease , neuroscience , psychology , dementia , disease , endocrinology , diabetes mellitus
Cerebral amyloid angiopathy (CAA) is a vascular neuropathology commonly reported in non-cognitively impaired (NCI), mild cognitive impairment, and Alzheimer's disease (AD) brains. However, it is unknown whether similar findings are present in non-demented elderly subjects.