Open AccessEFFECT OF NITROGEN-CONTAINING COMPOUNDS ON PERIPHERAL BLOOD PARAMETERS IN THE BACKGROUND OF EXPERIMENTAL PANCYTOPENIA
Author(s) -
L. K. Baktybayeva,
Guldana Daulet,
KaiJie Yu,
A. Ye. Malmakova,
G. A. Zazybin,
G. K. Satybaldyeva
Publication year - 2021
Publication title -
doklady nacionalʹnoj akademii nauk respubliki kazahstan
Language(s) - English
Resource type - Journals
eISSN - 2518-1483
pISSN - 2224-5227
DOI - 10.32014/2021.2518-1483.31
Subject(s) - hydrochloride , chemistry , fluorobenzene , pharmacology , biochemistry , organic chemistry , medicine , benzene
1-(2-phenylethyl)-4-ketoxympiperidine o-fluorobenzoic acid hydrochloride, a complex with β-cyclodextrin p-fluorobenzene carbonylamide morpholine, a complex with β-cyclodextrin o-fluorobenzene carbonylamide piperidine had high myelostimulating activity at the level of the comparison drug methyluracil. 1-(3-ethoxypropyl)-4-ketoxympiperidine p-fluorobenzoic acid ester hydrochloride, 1-(2-phenylethyl)-4-ketoxympiperidine m-fluorobenzoic acid ester hydrochloride, 1-(2-phenylethyl)-4-ketoxympiperidine p-fluorobenzoic acid ester hydrochloride did not possess leukopoiesis-stimulating activity, but showed erythropoiesis-stimulating and thrombocytopoiesis-stimulating activity at the level of the comparison drug methyluracil.