Open AccessMultifunctional ENY2 protein interacts with RNA helicase MLE
Author(s) -
J. V. Nikolenko,
М. М. Куршакова,
А. Н. Краснов
Publication year - 2019
Publication title -
doklady akademii nauk. rossijskaâ akademiâ nauk
Language(s) - English
Resource type - Journals
ISSN - 0869-5652
DOI - 10.31857/s0869-56524896637-640
Subject(s) - rna helicase a , helicase , drosophila melanogaster , gene , rna , biology , protein subunit , genetics , multiprotein complex , computational biology , protein–protein interaction , gene expression , microbiology and biotechnology
ENY2 protein of Drosophila melanogaster was previously discovered and characterized in our laboratory [1]. It was found that ENY2 is a subunit of several multiprotein complexes and connects various stages of gene expression [2-4]. This work is devoted to studying the interaction of ENY2 with RNA helicase MLE. This interaction was confirmed by independent methods. Data were obtained indicating that this interaction is conserved in evolution and is important for the functioning of MLE in both sexes.