Open AccessThe redox properties and antiradical activity of terpenophenols
Author(s) -
М. А. Половинкина,
M. N. Kolyada,
В. П. Осипова,
Н. Т. Берберова,
I. Yu. Chukicheva,
O. A. Shumova,
A. V. Kutchin
Publication year - 2019
Publication title -
doklady akademii nauk. rossijskaâ akademiâ nauk
Language(s) - English
Resource type - Journals
ISSN - 0869-5652
DOI - 10.31857/s0869-56524845568-571
Subject(s) - superoxide , redox , chemistry , antioxidant , oxidative stress , electron transfer , biochemistry , photochemistry , organic chemistry , enzyme
The redox properties and antiradical activity of terpenophenols (2,6-diisobornyl-4-methylphenol and 3-isocamphyl-2-naphthol) in comparison with BHT (butylhydroxytoluol, 2,6-di-tret-butyl-4-methylphenol) have been studied. The terpenophenols have been shown to react more readily in electron transfer processes as compared with BHT, and they have been found to react with electrochemically generated superoxide radical anion (О2•–). The effect of the compounds on the rate of generation upon adrenaline oxidation in an alkaline medium and the ability of biopreparations based on Russian sturgeon liver and gonad homogenates to deactivate have been studied. Adrenaline oxidation inhibition and the increase in superoxide dismutation activity of the biopreparations in the presence of terpenophenols have been shown, and this fact can indicate the ability of these compounds to decrease the probability of oxidative stress enlargement. A correlation has been established between the redox properties and antioxidant activity of terpenophenols in the model system of adrenaline oxidation in the presence of the biopreparations.