Open AccessEffect of transcription on the white gene enhancer integrated into the intron
Author(s) -
M. M. Erokhin,
А. В. Михайлова,
P. G. Georgiev,
Darya Chetverina
Publication year - 2019
Publication title -
doklady akademii nauk. rossijskaâ akademiâ nauk
Language(s) - English
Resource type - Journals
ISSN - 0869-5652
DOI - 10.31857/s0869-56524844495-497
Subject(s) - enhancer , intron , transcription (linguistics) , gene , enhancer rnas , transgene , biology , promoter , genetics , transcription factor , microbiology and biotechnology , gene expression , linguistics , philosophy
We demonstrate that passing-through transcription suppresses the activity of the white gene enhancer integrated into the intron. At the same time, the SV40 transcription terminators flanking the transgene can completely remove the inhibitory effect of transcription.