Open AccessISOLATION OF THE ACTIVE COMPOUND FROM THE BARK OF Cinnamomum burmanniiAS A SUNSCREEN
Author(s) -
R. Nasution,
D. Mailidar,
M. Bahi,
N. Saidi,
M. Marianne,
M. Iqhrammullah
Publication year - 2022
Publication title -
rasayan journal of chemistry/rasayan journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.281
H-Index - 22
eISSN - 0976-0083
pISSN - 0974-1496
DOI - 10.31788/rjc.2022.1516619
Subject(s) - lotion , chemistry , cinnamomum , ethyl acetate , solvent , chromatography , sun protection factor , cinnamaldehyde , organic chemistry , traditional medicine , dermatology , medicine , alternative medicine , traditional chinese medicine , pathology , cassia , catalysis
Our research aimed to extractCinnamomum burmannii stem barks usingethyl acetate solvent, which further followed by the investigation of for the sunscreen potential of the extract. Crude extract, subfraction, and pure isolate were used to prepare lotion formulations and tested for their sun protection factor (SPF) values. The results showed that lotionsprepared from the crude extract or its subfraction had effecacious sunscreen activity, reaching 38.15 ± 0.51. The pure isolate obtained was elucidated by analyzing the spectral data from 1H-Nuclear Magnetic Resonance (1HNMR), 13C-NMR, Mass Spectrometry, and Fourier-TransformInfrared Spectroscopy. The pure isolate wasfound to be 2-Propenoic acid, 3-(2-hydroxyphenyl)-, €- having an SPF value of 33.62 ± 0.62, where its lotion formulation had an SPF value of32.14 ± 0.97. Viscosity and pH properties of the prepared lotion met the criteria from the Indonesian National Standard with spreadability and adhesiveness that are convenient for topical application. Taken altogether, the lotions prepared from ethyl acetate extract of C. burmannii could potentially be used as sunscreen agents.