Open AccessCryptosomes: A Novel Promising Drug Delivery System
Author(s) -
Kanhaiya M. Dadure,
Animeshchandra G. M. Haldar
Publication year - 2017
Publication title -
international journal of medical and pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2231-685X
pISSN - 2231-2188
DOI - 10.31782/ijmps.2017.7101
Subject(s) - drug delivery , bioavailability , drug , pharmacology , vesicle , drug carrier , polyethylene glycol , liposome , chemistry , nanotechnology , peg ratio , carrier system , medicine , materials science , membrane , computer science , biochemistry , telecommunications , finance , economics
Vesicular drug delivery systems might be a solution to the problem of limited bioavailability and rapid clearance of medications from the body. The four kinds of lipid-based drug delivery techniques include solid-lipid particle system, emulsion-based system, solid lipid tablet, and vesicular system. Cryptosomes are a novel vesicular drug delivery system that may solve some of the shortcomings of classic drug delivery methods, such as high stability, enhanced bioavailability, longer release, and decreased elimination of fast metabolizable drugs, among others. Cryptosome is derived from the Greek terms “Crypto,” which means “hidden,” and “Soma,” which means “body.” It’s made up of phospholipids like distearoylphosphatidylethanolamine-polyethylene glycol and distearoylphosphatidylcholine (DSPE-PEG). Vesicular systems refer to the use of vesicles as a carrier or adjuvant in a variety of applications. This research looks at several vesicular drug delivery technologies and emphasises cryptosome’s accomplishments in this area. This review will be useful to researchers working in the field of vesicular drug delivery.